愛(ài)必信（absin)   abs50001   Annexin V-FITC/PI細(xì)胞凋亡檢測(cè)試劑盒，好用不貴、受到越來(lái)越多老師們的認(rèn)可，使用該產(chǎn)品發(fā)表在各類優(yōu)質(zhì)期刊上的文獻(xiàn)已經(jīng)多達(dá)52篇啦！

1、 產(chǎn)品原理及應(yīng)用

細(xì)胞凋亡早期，位于細(xì)胞膜脂質(zhì)雙層內(nèi)側(cè)的磷脂酰絲氨酸PS會(huì)從細(xì)胞膜內(nèi)側(cè)翻轉(zhuǎn)到細(xì)胞膜的表面，而鈣離子依賴型的Annexin V可與PS特異性結(jié)合；PI不能透過(guò)完整的細(xì)胞膜，凋亡中晚期細(xì)胞膜通透性增加、PI 得以透過(guò)細(xì)胞膜而使細(xì)胞核染紅。
將Annexin V-FITC 與PI 配合使用，可以有效區(qū)分處于不同凋亡時(shí)期的細(xì)胞。
abs50001 Annexin V-FITC/PI細(xì)胞凋亡檢測(cè)試劑盒既適用于流式細(xì)胞儀的定量研究，也可用于原位染色的定性研究。

2、 產(chǎn)品優(yōu)勢(shì)
1） 簡(jiǎn)便：只需分別加緩沖液、Annexin V-FITC和PI即可；
2） 快捷：從加緩沖液到上機(jī)只需20分鐘；
3） 靈敏：與熒光染料法等相比靈敏度更高、特異性更強(qiáng)。
abs50001 Annexin V-FITC/PI細(xì)胞凋亡檢測(cè)試劑盒與其他同類型產(chǎn)品相比，可有效減少流式實(shí)驗(yàn)時(shí)早期凋亡細(xì)胞與正常細(xì)胞的黏連情況，且非特異性結(jié)合較少、分群更為清晰。

3、 文獻(xiàn)展示

實(shí)驗(yàn)結(jié)果圖 [圖片來(lái)源于文獻(xiàn)內(nèi)容】

Three macrophage subsets are identified in the uterus during early human pregnancy 
Cell Mol Immunol. 2018 Apr 04 ; 12
影響因子： 8.483

Enzyme-instructed self-aggregation of Fe3O4 nanoparticles for enhanced MRI T2 imaging and photothermal therapy of tumors
Nanoscale. 2020 Jan 06 .
影響因子： 6.97

The apoptosis of MCF-7 cells after incubating with different liposomes for 48 h.

Tyrosine modified irinotecan-loaded liposomes capable of simultaneously targeting LAT1 and ATB0,+ for efficient tumor therapy J Control Release. 2019 Oct 30 .
影響因子： 7.901

Moderate mechanical stress suppresses the IL‐1β‐induced chondrocyte apoptosis by regulating mitochondrial dynamics
Journal of Cellular Physiology. 2021 Apr 06 .
影響因子： 5.547

Cimigenoside functions as a novel γ-secretase inhibitor and inhibits the proliferation or metastasis of human breast cancer cells by γ-secretase/Notch axis
Pharmacological Research. 2021 Feb 20 .
影響因子： 5.894

4-Methoxydalbergione is a potent inhibitor of human astroglioma U87 cells in vitro and in vivo
Acta Pharmacologica Sinica. 2020 Dec 11 .
影響因子： 5.064

lncRNA-ZFAS1 induces mitochondria-mediated apoptosis by causing cytosolic Ca2+ overload in myocardial infarction mice model 
Cell Death & Disease. 2019 Dec 09 .
影響因子： 6.303

Structure-based virtual screening and biological evaluation of novel non-bisphosphonate farnesyl pyrophosphate synthase inhibitors
EUR J MED CHEM. 2019 Nov 22 .
影響因子： 5.573

MRI-visible and pH-sensitive micelles loaded with doxorubicin for hepatoma treatment 
Biomaterials Science. 2019 Mar 26 ; 4
影響因子： 6.18

Codelivery of sorafenib and GPC3 siRNA with PEI-modified liposomes for hepatoma therapy 
Biomaterials science. 2017 Dec 23 ; 12
影響因子： 6.184

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